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clonidine hydrochloride cas no:4205-91-8

Synonyms: Clonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Identification
Nameclonidine hydrochloride
CAS4205-91-8
SynonymsClonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
EINECS(EC#)224-121-5
Molecular FormulaC9H9Cl2N3?HCl
Molecular Weight266.56
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T+:Verytoxic;
Risk R25;R26
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: coma, effects on sleep, fall in blood pressure, gastrointestinal system effects, increase in pulse rate, pulse rate decrease, reduced blood pressure, respiratory depression, respiratory system effects, somnolence. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Cl?.
Hazard Codes:?VeryT+
Risk Statements: 25-26?
R25 :Toxic if swallowed.?
R26:Very toxic by inhalation.
Safety Statements: 22-26-28-36/37/39-45?
S22:Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: NJ2490000
F: 10
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

orl-inf TDLo:390?μg/kg

??? PEDIAU ?? Pediatrics. 72 (1983),500.
2. ???

orl-wmn TDLo:180?μg/kg:BAH,CVS,PUL

??? AJEMEN ?? American Journal of Emergency Medicine. 7 (1989),343.
3. ???

orl-inf TDLo:390?μg/kg:NAH,CVS

??? PEDIAU ?? Pediatrics. 72 (1983),500.
4. ???

orl-wmn TDLo:126?μg/kg/4?W-I:GIT

??? BMJOAE ?? British Medical Journal. 292 (1986),174.
5. ???

orl-man TDLo:69?μg/kg:CNS,CVS

??? LANCAO ?? Lancet. 2 (1976),694.
6. ???

orl-chd TDLo:70?μg/kg:CNS,CVS,PUL

??? AJDCAI ?? American Journal of Diseases of Children. 137 (1983),171.
7. ???

orl-rat LD50:126?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
8. ???

ipr-rat LD50:100?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 9 (1978),829.
9. ???

scu-rat LD50:77?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
10. ???

ivn-rat LD50:29?mg/kg

??? ARZNAD ?? Arzneimittel-Forschung. Drug Research. 16 (1966),1038.
11.

supplier list

Saniver Limited
Tel:
Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.
Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
KOA SHOJI CO., LTD.
Tel:+81-45-540-6985
Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan
J.INC.
Tel:+91 79 30903703
Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India
CFM Oskar Tropitzsch
Tel:+49-(9231)-9619-0
Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,
Standard Chem. & Pharm. Co., Ltd.
Tel:+886-(6)-6362515
Address: P.O. Box 74, Hsin Ying, Tainan 730,
Biotrend Chemicals AG
Tel:+41-(44)-805 76 76
Address: Unterdorfstr. 21b, Wangen/Zuerich CH-8602,
Tocris Bioscience
Tel:+1-(800)-421-3701
Address: 16144 Westwoods Business Park, Ellisville, Missouri 63021,
Forehigh Trade and Industry Co., Ltd.
Tel:+86-(311)-85882468, 85812872
Address: 4th ,Floor Shenxing Building, Zhaiying Street, Shijiazhuang 050021,
Chemner Pharma
Tel:+86-(23)-62482345
Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,
Liven Pharmaceuticals
Tel:+91-(0)-9425442563
Address: 86/JM/3A, Saket Nagar, Bhopal, Madhya Pradesh 462 024,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
Changzhou Ilhang Fine Chemical Co., Ltd.
Tel:+86-(519)-85157016, 85882900
Address:
Parchem - Fine & Specialty Chemicals
Tel:+1-(914)-654-6800, 800-282-3982
Address: 415 Huguenot Street, New Rochelle, New York 10801,
Alfa Chem
Tel:+1-(516)-504-0059, 800-375-6869
Address: 2 Harbor Way, Kings Point, New York 11024,

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