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clonidine hydrochloride cas no:4205-91-8

Synonyms: Clonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Identification
Nameclonidine hydrochloride
CAS4205-91-8
SynonymsClonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
EINECS(EC#)224-121-5
Molecular FormulaC9H9Cl2N3?HCl
Molecular Weight266.56
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T+:Verytoxic;
Risk R25;R26
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: coma, effects on sleep, fall in blood pressure, gastrointestinal system effects, increase in pulse rate, pulse rate decrease, reduced blood pressure, respiratory depression, respiratory system effects, somnolence. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Cl?.
Hazard Codes:?VeryT+
Risk Statements: 25-26?
R25 :Toxic if swallowed.?
R26:Very toxic by inhalation.
Safety Statements: 22-26-28-36/37/39-45?
S22:Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: NJ2490000
F: 10
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

orl-inf TDLo:390?μg/kg

??? PEDIAU ?? Pediatrics. 72 (1983),500.
2. ???

orl-wmn TDLo:180?μg/kg:BAH,CVS,PUL

??? AJEMEN ?? American Journal of Emergency Medicine. 7 (1989),343.
3. ???

orl-inf TDLo:390?μg/kg:NAH,CVS

??? PEDIAU ?? Pediatrics. 72 (1983),500.
4. ???

orl-wmn TDLo:126?μg/kg/4?W-I:GIT

??? BMJOAE ?? British Medical Journal. 292 (1986),174.
5. ???

orl-man TDLo:69?μg/kg:CNS,CVS

??? LANCAO ?? Lancet. 2 (1976),694.
6. ???

orl-chd TDLo:70?μg/kg:CNS,CVS,PUL

??? AJDCAI ?? American Journal of Diseases of Children. 137 (1983),171.
7. ???

orl-rat LD50:126?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
8. ???

ipr-rat LD50:100?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 9 (1978),829.
9. ???

scu-rat LD50:77?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
10. ???

ivn-rat LD50:29?mg/kg

??? ARZNAD ?? Arzneimittel-Forschung. Drug Research. 16 (1966),1038.
11.

supplier list

Saniver Limited
Tel:
Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.
Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
IFFECT CHEMPHAR CO., LTD.
Tel:86-25-84679300
Address: 509, FuXin International Building, No.359 HongWu R
Ancheng Pharma Limited
Tel:+86-755-82713308
Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China
Gyma Laboratories Of America, Inc.
Tel:+1-516-933-0900
Address: 135 Cantiague Rock Rd.Westbury, NY 11590
S.I.M.S.s.r.l.
Tel:+39 055 863051
Address: Via Dante Da Castiglione ,850125 Floronce
FAITH EAGLE (LABORATORY) LTD.
Tel:(+86-755) 82851290
Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China
Healthy Life Pharma (P) Limited
Tel:+91-22-32403692/32459914
Address: 401, Richa, B-29, New Andheri Link Road, Andheri (W)
KOA SHOJI CO., LTD.
Tel:+81-45-540-6985
Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan
J.INC.
Tel:+91 79 30903703
Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India
Yunyang Group Co. Ltd.
Tel:+86-(511)-6980259, 6980388
Address: Economic Development Zone 8 on the 8th Latitude, Danyang, Jiangsu 212300,
CFM Oskar Tropitzsch
Tel:+49-(9231)-9619-0
Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,
Unichem Laboratories Ltd.
Tel:+91-(22)-2678 0643 / 2678 2644
Address: Prabhat Estate, Off S.V.Road,Jogeshwari (West), Mumbai, Maharashtra 400 102,
Standard Chem. & Pharm. Co., Ltd.
Tel:+886-(6)-6362515
Address: P.O. Box 74, Hsin Ying, Tainan 730,
Biotrend Chemicals AG
Tel:+41-(44)-805 76 76
Address: Unterdorfstr. 21b, Wangen/Zuerich CH-8602,

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