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clonidine hydrochloride cas no:4205-91-8

Synonyms: Clonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Identification
Nameclonidine hydrochloride
CAS4205-91-8
SynonymsClonidine Hcl; 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride
EINECS(EC#)224-121-5
Molecular FormulaC9H9Cl2N3?HCl
Molecular Weight266.56
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T+:Verytoxic;
Risk R25;R26
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: coma, effects on sleep, fall in blood pressure, gastrointestinal system effects, increase in pulse rate, pulse rate decrease, reduced blood pressure, respiratory depression, respiratory system effects, somnolence. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Cl?.
Hazard Codes:?VeryT+
Risk Statements: 25-26?
R25 :Toxic if swallowed.?
R26:Very toxic by inhalation.
Safety Statements: 22-26-28-36/37/39-45?
S22:Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: NJ2490000
F: 10
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

orl-inf TDLo:390?μg/kg

??? PEDIAU ?? Pediatrics. 72 (1983),500.
2. ???

orl-wmn TDLo:180?μg/kg:BAH,CVS,PUL

??? AJEMEN ?? American Journal of Emergency Medicine. 7 (1989),343.
3. ???

orl-inf TDLo:390?μg/kg:NAH,CVS

??? PEDIAU ?? Pediatrics. 72 (1983),500.
4. ???

orl-wmn TDLo:126?μg/kg/4?W-I:GIT

??? BMJOAE ?? British Medical Journal. 292 (1986),174.
5. ???

orl-man TDLo:69?μg/kg:CNS,CVS

??? LANCAO ?? Lancet. 2 (1976),694.
6. ???

orl-chd TDLo:70?μg/kg:CNS,CVS,PUL

??? AJDCAI ?? American Journal of Diseases of Children. 137 (1983),171.
7. ???

orl-rat LD50:126?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
8. ???

ipr-rat LD50:100?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 9 (1978),829.
9. ???

scu-rat LD50:77?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 18 (1987),366.
10. ???

ivn-rat LD50:29?mg/kg

??? ARZNAD ?? Arzneimittel-Forschung. Drug Research. 16 (1966),1038.
11.

supplier list

Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
Yunyang Group Co. Ltd.
Tel:+86-(511)-6980259, 6980388
Address: Economic Development Zone 8 on the 8th Latitude, Danyang, Jiangsu 212300,
CFM Oskar Tropitzsch
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Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,
Unichem Laboratories Ltd.
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Address: Prabhat Estate, Off S.V.Road,Jogeshwari (West), Mumbai, Maharashtra 400 102,
Standard Chem. & Pharm. Co., Ltd.
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Address: P.O. Box 74, Hsin Ying, Tainan 730,
Forehigh Trade and Industry Co., Ltd.
Tel:+86-(311)-85882468, 85812872
Address: 4th ,Floor Shenxing Building, Zhaiying Street, Shijiazhuang 050021,
Wuhan Pharma Chemical Co., Ltd.
Tel:+86-27-87711369
Address: 430071
Chemner Pharma
Tel:+86-(23)-62482345
Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,
Trust & We Co., Ltd.
Tel:86-21-61551611
Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.
Hangzhou Sage Chemical Co., Ltd.
Tel:86-571-86818502
Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road
Changzhou Ilhang Fine Chemical Co., Ltd.
Tel:+86-(519)-85157016, 85882900
Address:
Wuxi Mizat Chemical Technology Co., Ltd
Tel:+86-(510)-86106900
Address: No.205,zhencheng Road, HI-TECT District, Wuxi, Jiangsu,
Glorient (Xiamen) Impex Co., Ltd.
Tel:+86-(592)-559-7140
Address: Room B213, Xinxin Jingdi Plaza, No.396 Jia He Road, Xiamen 361009,
Wuhan jinnuo chemical Co., LTD
Tel:86 027 87661180 15071086303
Address: JianCun stone shipai ling class May 12
Jinlan Pharm-Drugs Technology Co., Limited
Tel:86-571-85829152
Address: Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang

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