4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)- cas no:476-70-0
Synonyms: 4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-;6aa-Aporphine-2,9-diol,1,10-dimethoxy- (8CI);Boldine (6CI,7CI);(+)-(S)-Boldine;(+)-2,9-Dihydroxy-1,10-dimethoxyaporphine;(+)-Boldine;(S)-(+)-Boldine;(S)-Boldine;1,10-Dimethoxy-6aa-aporphine-2,9-diol;
Name4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)-
CAS476-70-0
Synonyms4H-Dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (S)-;6aa-Aporphine-2,9-diol,1,10-dimethoxy- (8CI);Boldine (6CI,7CI);(+)-(S)-Boldine;(+)-2,9-Dihydroxy-1,10-dimethoxyaporphine;(+)-Boldine;(S)-(+)-Boldine;(S)-Boldine;1,10-Dimethoxy-6aa-aporphine-2,9-diol;
EINECS(EC#)207-509-9
Molecular FormulaC19H21NO4
Molecular Weight327.37
refractive index1.638
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn:Harmful;
Risk R22
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Safety information of Boldine (CAS NO.476-70-0):
Hazard Codes 
Xn
Risk Statements
22 Harmful if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
1 Keep locked up
20 When using, do not eat or drink
24/25 Avoid contact with skin and eyes
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36 Wear suitable protective clothing
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR 1544
WGK Germany 3
RTECS CE0750000
HazardClass 6.1(b)
PackingGroup III
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
145mg/kg (145mg/kg) |
|
United States Patent Document. Vol. #4185119, |
| mouse |
LD50 |
intravenous |
90mg/kg (90mg/kg) |
CARDIAC: CHANGE IN RATE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Annales Pharmaceutiques Francaises. Vol. 38, Pg. 537, 1980. |
| mouse |
LD50 |
oral |
450mg/kg (450mg/kg) |
CARDIAC: CHANGE IN RATE
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Annales Pharmaceutiques Francaises. Vol. 38, Pg. 537, 1980. |
