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Pregn-4-ene-3,20-dione,11,21-dihydroxy-, (11b)- cas no:50-22-6

Synonyms: Corticosterone(8CI);11,21-Dihydroxyprogesterone;11-Hydroxycorticoaldosterone;11b,21-Dihydroxypregn-4-ene-3,20-dione;11b,21-Dihydroxyprogesterone;17-Deoxycortisol;4-Pregnene-11b,21-diol-3,20-dione;Kendall's compound B;NSC 9705;Reichstein's substance H;

Identification
NamePregn-4-ene-3,20-dione,11,21-dihydroxy-, (11b)-
CAS50-22-6
SynonymsCorticosterone(8CI);11,21-Dihydroxyprogesterone;11-Hydroxycorticoaldosterone;11b,21-Dihydroxypregn-4-ene-3,20-dione;11b,21-Dihydroxyprogesterone;17-Deoxycortisol;4-Pregnene-11b,21-diol-3,20-dione;Kendall's compound B;NSC 9705;Reichstein's substance H;
EINECS(EC#)200-019-6
Molecular FormulaC21H30O4
Molecular Weight346.51
Chemical Properties
Appearancewhite to light yellow powder
refractive index1.575
storage tempStore at RT
Safety Data

Hazard Xi,N,Xn,T
Risk R43
Safety

An experimental teratogen. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and fumes.
 

Hazard Codes: HarmfulXnIrritantXiDangerousNToxicT
Risk Statements: 43-40
S40:To clean the floor and all objects contaminated by this material, use .... (there follows suitable cleaning material). 
S43:In case of fire use ... (there follows the type of fire-fighting equipment to be used.)
Safety Statements: 36-22
R22:Harmful if swallowed. 
R36:Irritating to eyes.


Toxicity
1.    

dni-rat:oth 100 nmol/L

    ECREAL    Experimental Cell Research. 161 (1985),29.
2.    

dni-ckn:emb 1500 pmol/L

    NATUAS    Nature. 257 (1975),804.

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