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Clomifene citrate cas no:50-41-9

Synonyms: Chloramiphene;Clomifene citrate (JP14);Clomivid;Ethanamine,2-[4-(2-chloro-1,2-diphenyl- ethenyl)phenoxy]-N,N-diethyl-,2-hydroxy-1,- 2,3-propanetricarboxylate (1:1);MRL-41;Clomid (TN);RMI 16312;Serophene citrate;2-[4-(2-chloro-1,2-diphenyl-ethenyl)phenoxy]-N,N-diethyl-ethanamine;Genozym;Clomphid;MRL 41;Fertyl;MER-41;Clomiphene dihydrogen citrate;Ikaclomin;Fertivet;Dyneric;Prestwick_757;Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, citrate;MER 41;clomifen dihydrogen citrate;

Identification
NameClomifene citrate
CAS50-41-9
SynonymsChloramiphene;Clomifene citrate (JP14);Clomivid;Ethanamine,2-[4-(2-chloro-1,2-diphenyl- ethenyl)phenoxy]-N,N-diethyl-,2-hydroxy-1,- 2,3-propanetricarboxylate (1:1);MRL-41;Clomid (TN);RMI 16312;Serophene citrate;2-[4-(2-chloro-1,2-diphenyl-ethenyl)phenoxy]-N,N-diethyl-ethanamine;Genozym;Clomphid;MRL 41;Fertyl;MER-41;Clomiphene dihydrogen citrate;Ikaclomin;Fertivet;Dyneric;Prestwick_757;Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-, citrate;MER 41;clomifen dihydrogen citrate;
EINECS(EC#)200-035-3
Molecular FormulaC26H28ClNO.C6H8O7
Molecular Weight598.14
Chemical Properties
AppearanceCrystalline Solid
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Safety Data

Hazard T:Toxic
Risk R60;R63
Safety

Hazard Codes:?ToxicT
Risk Statements: 60-63?
R60:May impair fertility.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 53-36/37-45?
S53:Avoid exposure - obtain special instructions before use.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: YE0875000
Moderately toxic by ingestion and intraperitoneal routes. Human reproductive effects by ingestion: changes in spermatogenesis and effects on testes, epididymis, and sperm duct. Human teratogenic effects by an unspecified route: developmental abnormalities of the eye and ear. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Used as a drug to induce ovulation and for the treatment of oligospermia. When heated to decomposition it emits very toxic fumes of Cl? and NOx.


Toxicity
1. ???

dnd-esc 25?mg/L

??? MUREAV ?? Mutation Research. 165 (1986),57.
2. ???

dni-esc 50?mg/L

??? MUREAV ?? Mutation Research. 165 (1986),57.
3. ???

orl-rat LD50:5750?mg/kg

??? TXAPA9 ?? Toxicology and Applied Pharmacology. 9 (1966),44.
4. ???

ipr-rat LD50:530?mg/kg

??? TXAPA9 ?? Toxicology and Applied Pharmacology. 9 (1966),44.
5. ???

orl-mus LD50:1700?mg/kg

??? OYYAA2 ?? Oyo Yakuri. Pharmacometrics. 3 (1969),187.

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SUZHOU UNITE PHARMACEUTICAL CO.,LTD.
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Chemner Pharma
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Conier Chem & Pharma Co.,Ltd.
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AOKChem Co., Ltd.
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Shanghai Xunxin Chemical Co., Ltd
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Facus Pharmaceutical Co., Ltd.
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Unite (Suzhou ) Pharmtech Co., Ltd.
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Hubei Sino Pharmaceuticals Co., Ltd.
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