Methylprednisolone acetate cas no:53-36-1
Synonyms: Pregna-1,4-diene-3,20-dione,11b,17,21-trihydroxy-6a-methyl-, 21-acetate (6CI,7CI,8CI);11b,17a,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-acetate;21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione;6-Methylprednisolone acetate;6a-Methylprednisolone 21-acetate;6a-Methylprednisolone acetate;DepMedalone 40;DepMedalone80;Depo-Medrate;Depo-Medrol;Depo-Medrone;Depo-methylprednisolone;Medrol acetate;Mepred;Methylprednisolone 21-acetate;Urbason Crystal Suspension;Vetacortyl;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6a,11b)-;
NameMethylprednisolone acetate
CAS53-36-1
SynonymsPregna-1,4-diene-3,20-dione,11b,17,21-trihydroxy-6a-methyl-, 21-acetate (6CI,7CI,8CI);11b,17a,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-acetate;21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione;6-Methylprednisolone acetate;6a-Methylprednisolone 21-acetate;6a-Methylprednisolone acetate;DepMedalone 40;DepMedalone80;Depo-Medrate;Depo-Medrol;Depo-Medrone;Depo-methylprednisolone;Medrol acetate;Mepred;Methylprednisolone 21-acetate;Urbason Crystal Suspension;Vetacortyl;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6a,11b)-;
EINECS(EC#)200-171-3
Molecular FormulaC24H32O6
Molecular Weight416.51
AppearanceOff-White Solid
refractive index1.58
storage tempRefrigerator
Safety
Poison by subcutaneous route. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it yields acrid smoke and fumes.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
> 1409mg/kg (1409mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 1182, 1990. |
| mouse |
LD50 |
subcutaneous |
1320mg/kg (1320mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 10(Suppl, |
| rat |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 1182, 1990. |
| rat |
LD50 |
subcutaneous |
265mg/kg (265mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 10(Suppl, |
