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cantharidin cas no:56-25-7

Synonyms: Dimethyl-3,6-epoxyperhydrophthalic anhydride; (1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride

Identification
Namecantharidin
CAS56-25-7
SynonymsDimethyl-3,6-epoxyperhydrophthalic anhydride; (1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride
EINECS(EC#)200-263-3
Molecular FormulaC10H12O4
Molecular Weight196.2
Chemical Properties
AppearanceWhite crystals.
refractive index1.547
storage tempKeep in a sealed container. Place in a poison cabinet with controlled access.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T+:Verytoxic;
Risk R28;R36/37/38
Safety

Hazard Codes?T+T
Risk Statements 28-36/37/38-23/24/25
?R28:Very toxic if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements 53-45-36/37/39
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS RN8575000
HazardClass 6.1(a)
PackingGroup I


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 310mg/kg (310mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
chicken LDLo subcutaneous 75mg/kg (75mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
dog LDLo oral 50mg/kg (50mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
frog LDLo oral 7273mg/kg (7273mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
human LDLo oral 428ug/kg (0.428mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 646, 1969.
mammal (species unspecified) LD50 intraperitoneal 1710ug/kg (1.71mg/kg) ? "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher,Peop. Rep. China, 1994Vol. -, Pg. 183, 1994.
mammal (species unspecified) LDLo oral 75mg/kg (75mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
mammal (species unspecified) LDLo unreported 50mg/kg (50mg/kg) ? Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 20, Pg. 135, 1989.
mouse LD50 intraperitoneal 1mg/kg (1mg/kg) ? Journal of Agricultural and Food Chemistry. Vol. 35, Pg. 823, 1987.
pigeon LDLo oral 32mg/kg (32mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit LDLo oral 20mg/kg (20mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) Toxicon. Vol. 23, Pg. 36, 1985.
rabbit LDLo subcutaneous 1mg/kg (1mg/kg) ? "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.

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