57-62-5|ChlorotetracyclineProducts Supply - Chemical intermediates Network

Chlorotetracycline cas no:57-62-5

Synonyms: 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(7CI,8CI);2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5aa,6b,12aa)]-;Aureomicina;Aureomycin;Aureomykoin;Aurofac;Aureocina;A-Mycin;Acronize;7-Chlorotetracycline;7-Chlortetracycline;Tri-chlortetracycline;Acronize PD;Chrysomykine;Chlortetracycline;Centraureo;Chlorocyclinum;

Identification

NameChlorotetracycline
CAS57-62-5
Synonyms2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(7CI,8CI);2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5aa,6b,12aa)]-;Aureomicina;Aureomycin;Aureomykoin;Aurofac;Aureocina;A-Mycin;Acronize;7-Chlorotetracycline;7-Chlortetracycline;Tri-chlortetracycline;Acronize PD;Chrysomykine;Chlortetracycline;Centraureo;Chlorocyclinum;
EINECS(EC#)200-341-7
Molecular FormulaC₂₂H₂₃ClN₂O₈
Molecular Weight478.88

Chemical Properties

AppearanceGolden yellow crystal powder
refractive index1.745
storage temp2-8°C

Safety Data

Hazard Xn
Risk R22
Safety

Hazard Codes:? Xn
Risk Statements:? 22
22:?Chlorotetracycline (57-62-5) is harmful if swallowed?
RTECS:? QI7750000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	150mg/kg (150mg/kg)	?	"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 52, 1959.
dog	LD50	oral	750mg/kg (750mg/kg)	?	Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
guinea pig	LDLo	intraperitoneal	1800mg/kg (1800mg/kg)	?	Antibiotiki. Vol. 20, Pg. 793, 1975.
mouse	LD50	intracrebral	48mg/kg (48mg/kg)	behavioral: "hallucinations, distorted perceptions" behavioral: excitement musculoskeletal: changes in teeth and supporting structures	Chemotherapy Vol. 26, Pg. 196, 1980.
mouse	LD50	intravenous	134mg/kg (134mg/kg)	?	Antibiotics and Chemotherapy Vol. 6, Pg. 623, 1956.
mouse	LD50	oral	1500mg/kg (1500mg/kg)	?	Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
mouse	LDLo	intraperitoneal	192mg/kg (192mg/kg)	?	Compilation of LD50 Values of New Drugs.
mouse	LDLo	subcutaneous	3gm/kg (3000mg/kg)	?	Antibiotics and Chemotherapy Vol. 6, Pg. 623, 1956.
rat	LD50	intravenous	118mg/kg (118mg/kg)	?	Antibiotics and Chemotherapy Vol. 6, Pg. 623, 1956.
rat	LDLo	intraperitoneal	335mg/kg (335mg/kg)	?	Compilation of LD50 Values of New Drugs.
rat	LDLo	oral	3gm/kg (3000mg/kg)	?	Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 497, 1969.

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Manus Aktteva: Tel:+91-(79)-65123395; Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006,

Beijing HuameiHuli Biochem Ltd: Tel:010-86181995; Address: Beijing TongZhou District

Chlorotetracycline cas no:57-62-5

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