57333-96-7|TacalcitolProducts Supply - Chemical intermediates Network

Tacalcitol cas no:57333-96-7

Synonyms: 9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol,(1a,3b,5Z,7E,24R)- (9CI);1a,24(R)-Dihydroxycholecalciferol;1a,24R-Dihydroxyvitamin D3;Bonalfa;Curatoderm;PRI 2191;TV 02;

Identification

NameTacalcitol
CAS57333-96-7
Synonyms9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol,(1a,3b,5Z,7E,24R)- (9CI);1a,24(R)-Dihydroxycholecalciferol;1a,24R-Dihydroxyvitamin D3;Bonalfa;Curatoderm;PRI 2191;TV 02;
Molecular FormulaC₂₇H₄₄O₃
Molecular Weight416.71

Chemical Properties

refractive index1.545
storage tempStore at -20°C

Safety Data

Safety

A poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	subcutaneous	10ug/kg (0.01mg/kg)	BEHAVIORAL: FOOD INTAKE (ANIMAL) BLOOD: "CHANGES IN SERUM COMPOSITION (E.G., TP, BILIRUBIN, CHOLESTEROL)"	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
mouse	LD50	intravenous	559ug/kg (0.559mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
mouse	LD50	oral	3050ug/kg (3.05mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
mouse	LD50	subcutaneous	419ug/kg (0.419mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
rat	LD50	intravenous	556ug/kg (0.556mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
rat	LD50	oral	3279ug/kg (3.279mg/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
rat	LD50	subcutaneous	100ug/kg (0.1mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.
rat	LD50	subcutaneous	100ug/kg (0.1mg/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 17, Pg. 4615, 1989.

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Tacalcitol cas no:57333-96-7

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