58-71-9|5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt(1:1), (6R,7R)-Products Supply

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt(1:1), (6R,7R)- cas no:58-71-9

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt,(6R-trans)-;Averon 1;Cefalothine sodium;Cemastin;Cephalothin sodium salt;Cephation;Ceporacin;Cepovenin;Coaxin;Keflin;Lilly 38253;Lospoven;Microtin;Seffin;Sodium(thienylacetamido)cephalosporanate;Sodium 3-acetoxymethyl-7b-(2-thienylacetamido)ceph-3-em-4-carboxylate;Sodium 7-(2-thienylacetamido)-3-acetoxymethyl-3-cephem-4-carboxylate;Sodium7-[2-(2-thienyl)acetamido]cephalosporanate;Sodium cefalotin;Sodiumcephalothin;Sodium cephalotin;Synclotin;Toricelocin;

Identification

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt(1:1), (6R,7R)-
CAS58-71-9
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt,(6R-trans)-;Averon 1;Cefalothine sodium;Cemastin;Cephalothin sodium salt;Cephation;Ceporacin;Cepovenin;Coaxin;Keflin;Lilly 38253;Lospoven;Microtin;Seffin;Sodium(thienylacetamido)cephalosporanate;Sodium 3-acetoxymethyl-7b-(2-thienylacetamido)ceph-3-em-4-carboxylate;Sodium 7-(2-thienylacetamido)-3-acetoxymethyl-3-cephem-4-carboxylate;Sodium7-[2-(2-thienyl)acetamido]cephalosporanate;Sodium cefalotin;Sodiumcephalothin;Sodium cephalotin;Synclotin;Toricelocin;
EINECS(EC#)200-394-6
Molecular FormulaC₁₆H₁₅N₂NaO₆S₂
Molecular Weight418.41

Chemical Properties

AppearanceOdour
storage temp2-8°C

Safety Data

Hazard Xn: Harmful;
Risk R42/43
Safety

Human systemic effects by intravenous and intramuscular routes: blood agranulocytosis and thrombocytopenia. When heated to decomposition it emits very toxic fumes of NO_x, SO_x, and Na₂O.

Risk Statements:42/43:? May cause sensitization by inhalation and skin contact?
Safety Statements:22:? Do not breathe dust;36/37:? Wear suitable protective clothing and gloves?
Hazard Codes:Xn,Xi
WGK Germany:2

HS Code 29419000

Toxicity

1.	???	ivn-wmn TDLo:20?mg/kg:BLD	???	AIMEAS ?? Annals of Internal Medicine. 77 (1972),401.
2.	???	ims-chd TDLo:89?mg/kg/19D-I:BLD AACHAX -,272,63
3.	???	ims-man TDLo:955?mg/kg/22D-I:BLD AACHAX -,272,63
4.	???	ipr-rat LD50:7000?mg/kg	???	JJANAX ?? Japanese Journal of Antibiotics. 28 (1975),188.
5.	???	scu-rat LD50:7500?mg/kg	???	JIDIAQ ?? Journal of Infectious Diseases. 137 (1978),S51.
6.	???	ipr-mus LD50:5670?mg/kg	???	JJANAX ?? Japanese Journal of Antibiotics. 27 (1974),746.
7.	???	scu-mus LD50:7500?mg/kg	???	JACHDX ?? Journal of Antimicrobial Chemotherapy. 6 (Suppl A),(1980),79.
8.	???	ivn-mus LD50:4800?mg/kg	???	JJANAX ?? Japanese Journal of Antibiotics. 27 (1974),746.

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5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt(1:1), (6R,7R)- cas no:58-71-9

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