63516-07-4|Flutropium Bromide HydrateProducts Supply

Flutropium Bromide Hydrate cas no:63516-07-4

Synonyms: Flutropium Bromide;Flutropium;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (3-Endo,8-Syn)-;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (Endo,Syn)-;Ba 598br;Flubron;Ba 598;Flutropiumbromid;

Identification

NameFlutropium Bromide Hydrate
CAS63516-07-4
SynonymsFlutropium Bromide;Flutropium;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (3-Endo,8-Syn)-;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (Endo,Syn)-;Ba 598br;Flubron;Ba 598;Flutropiumbromid;
Molecular FormulaC₂₄H₂₉BrFNO₃
Molecular Weight478.39

Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x, Br⁻, and Cl⁻.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	53mg/kg (53mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
mouse	LD50	intravenous	11mg/kg (11mg/kg)	behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea behavioral: ataxia	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse	LD50	oral	760mg/kg (760mg/kg)	behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse	LD50	subcutaneous	228mg/kg (228mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat	LD50	intraperitoneal	77mg/kg (77mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat	LD50	intravenous	12500ug/kg (12.5mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat	LD50	oral	740mg/kg (740mg/kg)	behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
rat	LD50	subcutaneous	615mg/kg (615mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.

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Flutropium Bromide Hydrate cas no:63516-07-4

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