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Aureomycin hydrochloride;Chlortetracycline hydrochloride cas no:64-72-2

Synonyms: 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride (8CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, (4S,4aS,5aS,6S,12aS)- (9CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5aa,6b,12aa)]-; 7-Chlorotetracyclinehydrochloride; 7-Chlorotetracycline monohydrochloride; Aureociclina;Aureocycline; Aureomycin hydrochloride; Aureomycin monohydrochloride; Aureovit12C80; Aurofac 100; Biomycin hydrochloride; Chlortetracycline hydrochloride;Chlortetracyclinium chloride; Fermycin Soluble; Isphamycin; NSC 13252

Identification
NameAureomycin hydrochloride;Chlortetracycline hydrochloride
CAS64-72-2
Synonyms2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride (8CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, (4S,4aS,5aS,6S,12aS)- (9CI); 2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5aa,6b,12aa)]-; 7-Chlorotetracyclinehydrochloride; 7-Chlorotetracycline monohydrochloride; Aureociclina;Aureocycline; Aureomycin hydrochloride; Aureomycin monohydrochloride; Aureovit12C80; Aurofac 100; Biomycin hydrochloride; Chlortetracycline hydrochloride;Chlortetracyclinium chloride; Fermycin Soluble; Isphamycin; NSC 13252
EINECS(EC#)200-591-7
Molecular FormulaC22H23ClN2O8?HCl
Molecular Weight515.35
Chemical Properties
Appearanceodorless yellow solid
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xi
Risk 36/37/38
Safety

Risk Statements:? 36/37/38
36/37/38:?Chlortetracycline hydrochloride (64-72-2) is?irritating to eyes, respiratory system and skin?
Safety Statements:? 26-36
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:? Wear suitable protective clothing?
WGK Germany:? 2
RTECS : QI7800000


Toxicity

Organism

Test Type

Route

Reported Dose (Normalized Dose)

Effect

Source

cat

LD

intravenous

> 50mg/kg (50mg/kg)

gastrointestinal: nausea or vomiting

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

dog

LDLo

intravenous

150mg/kg (150mg/kg)

behavioral: tremor
lungs, thorax, or respiration: dyspnea
kidney, ureter, and bladder: hematuria

Annals of the New York Academy of Sciences. Vol. 51, Pg. 254, 1948.

guinea pig

LD

subcutaneous

> 300mg/kg (300mg/kg)

?

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

guinea pig

LDLo

intravenous

100mg/kg (100mg/kg)

?

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

mouse

LD50

intraperitoneal

197mg/kg (197mg/kg)

?

Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 278, 1970.

mouse

LD50

intravenous

100mg/kg (100mg/kg)

?

Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 95, 1964.

mouse

LD50

oral

2314mg/kg (2314mg/kg)

?

Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 95, 1964.

mouse

LDLo

subcutaneous

400mg/kg (400mg/kg)

?

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

rabbit

LD

intravenous

> 50mg/kg (50mg/kg)

?

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

rat

LD

oral

> 3gm/kg (3000mg/kg)

?

Annals of the New York Academy of Sciences. Vol. 51, Pg. 182, 1948.

rat

LD50

intraperitoneal

335mg/kg (335mg/kg)

behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: respiratory stimulation

Antibiotics Annual. Vol. 1, Pg. 63, 1953/1954.

rat

LD50

intravenous

100mg/kg (100mg/kg)

?

Bollettino Chimico Farmaceutico. Vol. 102, Pg. 660, 1963.

supplier list

Wuhan Taiyicheng Biopharmaceutical Co., Ltd.
Tel:
Address: 7#, Meijiashan, Wuchang District, Wuhan, Hubei province, China
Kunshan Chemical Group (Industries) Corp.
Tel:+86-(520)-7303362
Address: No.21 Chao Yang Subroad, Kunshan, Jiangsu 215300,
Applichem GmbH
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Address: 4, Ottoweg, Darmstadt 64291,
AMRESCO Inc.
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Address: 30175 Solon Induatrial Parkway, Solon, Ohio 44139,
Ningbo Pangs Chem Int'l Co. Ltd.
Tel:+86-(574)-27668808
Address: Floor 21, Building 11, Xintiandi, No. 689, Shiji Road, Ningbo 315040,
Wuhan Pharma Chemical Co., Ltd.
Tel:+86-27-87711369
Address: 430071
Chemner Pharma
Tel:+86-(23)-62482345
Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,
Shanghai Xunxin Chemical Co., Ltd
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Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315,
Choriway International Trade Co., Ltd.
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Address: Room 716, No. 126. Quanchang Road, Wuxi, Jigansu 214043,
Alfa Chem
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Address: 2 Harbor Way, Kings Point, New York 11024,
BSM Chemical Import & Export Co.,Ltd.
Tel:0574-56708601
Address: 702 Zhongning Building , No.255 Lingqiao Road , Ningbo China
Dalian Huitong International Co., Ltd
Tel:+86-0411-39756198,39792808,84800785
Address: Rm1201,Xinghaiwangzuo Building,no.572 Zhongshan road,Dalian,China
KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD
Tel:86-23-8650081
Address: 32F,Duhe Plaza, Lijiatuo Street, Banan Dist,Chongq
Kingland Chemicals Company Limited
Tel:+86-571-87211518,87229835
Address: Room No. 1806-1808, Jinfeng Mansion, No.281 Zhong He Zhong Road, Hangzhou, China.
LIANYUNGANG RUNHOU INT'L TRADING CO LTD
Tel:86--0518--85476985
Address: NO.9-216 YIPINYUAN.JULONG(N)58#.LIANYUNGANG--222001.CHINA.

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