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Pregn-4-ene-3,20-dione,21-hydroxy- cas no:64-85-7

Synonyms: 11-Deoxycorticosterone(8CI);11-Dehydroxycorticosterone;11-Desoxycorticosterone;21-Hydroxy-3,20-dioxopregn-4-ene;21-Hydroxy-D4-pregnane-3,20-dione;21-Hydroxy-D4-pregnene-3,20-dione;21-Hydroxypregn-4-ene-3,20-dione;21-Hydroxyprogesterone;4-Pregnen-21-ol-3,20-dione;Cortexone;Corticosterone, 11-deoxy-;DOC;DOC(steroid);Deoxycorticosterone;Deoxycortone;Desoxycorticosterone;Desoxycortone;Kendall's desoxy compound B;NSC 11319;Reichstein's substanceQ;D4-Pregnene-21-ol-3,20-dione;

Identification
NamePregn-4-ene-3,20-dione,21-hydroxy-
CAS64-85-7
Synonyms11-Deoxycorticosterone(8CI);11-Dehydroxycorticosterone;11-Desoxycorticosterone;21-Hydroxy-3,20-dioxopregn-4-ene;21-Hydroxy-D4-pregnane-3,20-dione;21-Hydroxy-D4-pregnene-3,20-dione;21-Hydroxypregn-4-ene-3,20-dione;21-Hydroxyprogesterone;4-Pregnen-21-ol-3,20-dione;Cortexone;Corticosterone, 11-deoxy-;DOC;DOC(steroid);Deoxycorticosterone;Deoxycortone;Desoxycorticosterone;Desoxycortone;Kendall's desoxy compound B;NSC 11319;Reichstein's substanceQ;D4-Pregnene-21-ol-3,20-dione;
EINECS(EC#)200-596-4
Molecular FormulaC21H30O3
Molecular Weight330.51
Chemical Properties
Appearancewhite to creamy-white crystalline powder
alpha184 º (C=1, C2H5OH)
refractive index1.559
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
Safety Data

Hazard Xn: Harmful;
Risk R40;R48
Safety

Moderately toxic by unspecified route. Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
Xn: Harmful
Risk Statements about 11-Deoxycorticosterone (64-85-7):
R40 Limited evidence of a carcinogenic effect.
R48 Danger of serious damage to health by prolonged exposure.
Safety Statements about 11-Deoxycorticosterone (64-85-7):
S22 Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
Attentions:
1. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
2. Handling: Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation.


Toxicity
1.    

unr-mus LD50:1000 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 7 (1964),673.

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