9,10-Anthracenedione,1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]- cas no:65271-80-9
Synonyms: 1,4-Bis[(2-(2-hydroxyethylamino)ethyl)amino]-5,8-dihydroxyanthraquinone;1,4-Dihydroxy-5,8-bis-[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone;1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione;DHAQ;Dihydroxyanthraquinone;Mitoxanthrone;Mitoxantrone;Mitozantrone;NSC 279836;Novantron;Ralenova;
Name9,10-Anthracenedione,1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-
CAS65271-80-9
Synonyms1,4-Bis[(2-(2-hydroxyethylamino)ethyl)amino]-5,8-dihydroxyanthraquinone;1,4-Dihydroxy-5,8-bis-[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone;1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione;DHAQ;Dihydroxyanthraquinone;Mitoxanthrone;Mitoxantrone;Mitozantrone;NSC 279836;Novantron;Ralenova;
EINECS(EC#)274-619-1
Molecular FormulaC22H28N4O6
Molecular Weight444.48
Appearanceblue powder
refractive index1.709
storage temp-20°C Freezer
Hazard UN NO.
Risk R46
Safety
Poison by subcutaneous, intravenous, and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
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Hazard Codes: T.gif)
,T+
Risk Statements:
26: ?Very Toxic by inhalation
27: ?Very Toxic in contact with skin
28: ?Very Toxic if swallowed
46: ?May cause heritable genetic damage
61: ?May cause harm to the unborn child
Safety Statements:
22: ?Do not breathe dust
36: ?Wear suitable protective clothing?
37: ?Wear suitable gloves
39: ?Wear eye/face protection
45: ?In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53: ?Avoid exposure - obtain special instruction before use
| 1. |
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mmo-sat 20?μg/plate
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TCMUD8 ?? Teratogenesis, Carcinogenesis, and Mutagenesis. 5 (1985),319. |
| 2. |
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cyt-hmn:lym 100 μmol/L
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MUREAV ?? Mutation Research. 93 (1982),185. |
| 3. |
??? |
ipr-mus LD50:7100?μg/kg
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HYDXET ?? Huaxi Yike Daxue Xuebao. Journal of West China University of Medical Sciences. 20 (1989),303. |
| 4. |
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scu-mus LD50:20,910?μg/kg
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NCISP* ?? National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . |
| 5. |
??? |
ivn-mus LD50:6600?μg/kg
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HYDXET ?? Huaxi Yike Daxue Xuebao. Journal of West China University of Medical Sciences. 20 (1989),303. |
