2H-1-Benzopyran-2-one,3,3'-methylenebis[4-hydroxy- cas no:66-76-2

Name2H-1-Benzopyran-2-one,3,3'-methylenebis[4-hydroxy-
CAS66-76-2
SynonymsCoumarin,3,3'-methylenebis[4-hydroxy- (8CI);3,3'-Methylenebis[4-hydroxy-1,2-benzopyrone]; 3,3'-Methylenebis[4-hydroxycoumarin];Acadyl; Acavyl; Antitrombosin; Baracoumin; Bis(4-hydroxycoumarin-3-yl)methane;Bis-3,3'-(4-hydroxycoumarinyl)methane; Bishydroxycoumarin; Cuma; Cumid;Di-4-hydroxy-3,3'-methylenedicoumarin; Dicoumal; Dicoumarin; Dicoumarol;Dicuman; Dicumarine; Dicumarol; Dicumol; Dufalone; Kumoran; Melitoxin; NC 034;NSC 17860; NSC 221570; NSC 41834; Temparin; Trombosan
EINECS(EC#)200-632-9
Molecular FormulaC19H12 O6
Molecular Weight336.31

refractive index1.731

Hazardclass6.1(b)

Hazard T,N
Risk R22;R48/25;R51/53
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Human reproductive effects by ingestion and possibly other routes: fetal death, unspecified developmental abnormalities, stillbirth, and unspecified neonatal effects. An anticoagulant. Excessive doses can cause hemorrhages. When heated to decomposition it emits acrid smoke and fumes.

Hazard Codes:  T,N  
Risk Statements:  22-48/25-51/53 (R22:Harmful if swallowed. R48:Danger of serious damage to health by prolonged exposure. R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.)
Safety Statements:  37-45-61 (S37:Wear suitable gloves. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61:Avoid release to the environment. Refer to special instructions / safety data sheets.)
RIDADR:  UN 2811 6.1/PG 3
WGK Germany:  3
HazardClass:  6.1(b)
PackingGroup:  III

1.		orl-rat LD50:250 mg/kg		SMWOAS    Schweizerische Medizinische Wochenschrift. 83 (1953),471.
2.		ivn-rat LD50:52 mg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 50 (1942),228.
3.		orl-mus LD50:233 mg/kg		PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 50 (1942),228.
4.		ipr-mus LD50:91 mg/kg		DIPHAH    Dissertationes Pharmaceuticae. 17 (1965),163.
5.		scu-mus LD50:50 mg/kg		85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 8 (1)(1982),360.
6.		ivn-mus LD50:42 mg/kg		AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 222 (1954),107.

RTECS:  GN7875000