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Pergolide mesylate salt cas no:66104-23-2

Synonyms: Ergoline,8-[(methylthio)methyl]-6-propyl-,(8a)-,monomethanesulfonate;Prestwick_652;Pergolide mesilate;MPE;Permax (TN);Pergolide mesylate [USAN];Ergoline, 8-((methylthio)methyl)-6-propyl-, (8beta)-;LY127809;Ergoline, 8-[ (methylthio)methyl]-6-propyl-, (8.beta.)-, monomethanesulfonate;Pergolida [INN-Spanish];Pergolide mesilate (JAN);Permax;Pergolide mesylate (USP);Ergoline, 8-beta-((methylthio)methyl)-6-propyl-, methanesulfonate (1:1);Pergolidum [INN-Latin];8-.beta.-[(Methylthio)methyl]-6-propylergoline methanesulfonate;8-beta-((Methylthio)methyl)-6-propylergoline monomethane sulfonate;Pergolide mesilate salt;

Identification
NamePergolide mesylate salt
CAS66104-23-2
SynonymsErgoline,8-[(methylthio)methyl]-6-propyl-,(8a)-,monomethanesulfonate;Prestwick_652;Pergolide mesilate;MPE;Permax (TN);Pergolide mesylate [USAN];Ergoline, 8-((methylthio)methyl)-6-propyl-, (8beta)-;LY127809;Ergoline, 8-[ (methylthio)methyl]-6-propyl-, (8.beta.)-, monomethanesulfonate;Pergolida [INN-Spanish];Pergolide mesilate (JAN);Permax;Pergolide mesylate (USP);Ergoline, 8-beta-((methylthio)methyl)-6-propyl-, methanesulfonate (1:1);Pergolidum [INN-Latin];8-.beta.-[(Methylthio)methyl]-6-propylergoline methanesulfonate;8-beta-((Methylthio)methyl)-6-propylergoline monomethane sulfonate;Pergolide mesilate salt;
Molecular FormulaC19H26N2S.CH4O3S
Molecular Weight409.63
Chemical Properties
AppearanceWhite to Off-White Solid
storage temp?20°C
Safety Data

Hazard T+: Very toxic;
Risk R28
Safety

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also SULFONATES.
Hazard Codes:
T+: Very toxic
Risk Statements about 8-β-((Methylthio)methyl)-6-propyler-goline methanesulfonate (66104-23-2):
R28 Very toxic if swallowed.
Safety Statements about 8-β-((Methylthio)methyl)-6-propyler-goline methanesulfonate (66104-23-2):
S28 After contact with skin, wash immediately with plenty of soap-suds.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.


Toxicity
1.    

orl-rat LD50:15 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 48 (1979),A95.
2.    

orl-mus LD50:54 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 48 (1979),A95.
3.    

ipr-mus LD50:100 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 26 (1983),522.

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