69712-56-7|CefotetanProducts Supply - Chemical intermediates Network

Cefotetan cas no:69712-56-7

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,[6R-(6a,7a)]-;Apacef;

Identification

NameCefotetan
CAS69712-56-7
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,[6R-(6a,7a)]-;Apacef;
EINECS(EC#)274-093-3
Molecular FormulaC₁₇H₁₇N₇O₈S₄
Molecular Weight575.62

Chemical Properties

AppearanceOff-white solid
refractive index1.921
storage tempStore at 0-5°C

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 6gm/kg (6000mg/kg)		Yakkyoku. Pharmacy. Vol. 35, Pg. 2033, 1984.
mouse	LD50	intraperitoneal	8120mg/kg (8120mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LIVER: OTHER CHANGES	Chemotherapy Vol. 30(Suppl,
mouse	LD50	intravenous	4990mg/kg (4990mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: CHANGES IN SPLEEN	Chemotherapy Vol. 30(Suppl,
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Chemotherapy Vol. 30(Suppl,
rat	LD50	intraperitoneal	8250mg/kg (8250mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: CHANGES IN SPLEEN	Chemotherapy Vol. 30(Suppl,
rat	LD50	intravenous	5gm/kg (5000mg/kg)		"Current Chemotherapy and Infectious Diseases, Proceedings of the 11th International Congress of Chemotherapy and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA, 1979," Washington, DC, American Soc. for Microbiology, 1980Vol. 1, Pg. 273, 1980.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Chemotherapy Vol. 30(Suppl,

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Shanghai Hao Su Chem-Tech lnc.: Tel:021-6661 0036 021-5653 8833; Address: 201-204,2 BLDG,1009 North Zhong Shan Road, Shanghai

Cefotetan cas no:69712-56-7

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