dog |
LD50 |
intravenous |
> 6gm/kg (6000mg/kg) |
|
Yakkyoku. Pharmacy. Vol. 35, Pg. 2033, 1984. |
mouse |
LD50 |
intraperitoneal |
8120mg/kg (8120mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LIVER: OTHER CHANGES |
Chemotherapy Vol. 30(Suppl, |
mouse |
LD50 |
intravenous |
4990mg/kg (4990mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BLOOD: CHANGES IN SPLEEN |
Chemotherapy Vol. 30(Suppl, |
mouse |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Chemotherapy Vol. 30(Suppl, |
mouse |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
BEHAVIORAL: TREMOR
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 30(Suppl, |
rat |
LD50 |
intraperitoneal |
8250mg/kg (8250mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BLOOD: CHANGES IN SPLEEN |
Chemotherapy Vol. 30(Suppl, |
rat |
LD50 |
intravenous |
5gm/kg (5000mg/kg) |
|
"Current Chemotherapy and Infectious Diseases, Proceedings of the 11th International Congress of Chemotherapy and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA, 1979," Washington, DC, American Soc. for Microbiology, 1980Vol. 1, Pg. 273, 1980. |
rat |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Chemotherapy Vol. 30(Suppl, |
rat |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
BEHAVIORAL: TREMOR
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 30(Suppl, |