77174-66-4|1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, hydrochloride (1:1)Products Supply

1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, hydrochloride (1:1) cas no:77174-66-4

Synonyms: 1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, monohydrochloride (9CI);710674S;Croconazole hydrochloride;Croconazole monohydrochloride;Pilzcin;

Identification

Name1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, hydrochloride (1:1)
CAS77174-66-4
Synonyms1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, monohydrochloride (9CI);710674S;Croconazole hydrochloride;Croconazole monohydrochloride;Pilzcin;
Molecular FormulaC18H15 Cl N2 O . Cl H
Molecular Weight347.24

Safety Data

Safety

Moderately toxic by ingestion, skin contact, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	94mg/kg (94mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
mouse	LD50	oral	1150mg/kg (1150mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
mouse	LD50	subcutaneous	1gm/kg (1000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
rabbit	LD	skin	> 320mg/kg (320mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4847, 1984.
rabbit	LDLo	subcutaneous	1715mg/kg (1715mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4821, 1984.
rat	LD50	intraperitoneal	204mg/kg (204mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
rat	LD50	oral	2gm/kg (2000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
rat	LD50	skin	> 600mg/kg (600mg/kg)		Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.
rat	LD50	subcutaneous	4700mg/kg (4700mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 4811, 1984.

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1H-Imidazole,1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-, hydrochloride (1:1) cas no:77174-66-4

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