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Deoxycholic acid cas no:83-44-3

Synonyms: 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oic acid

Identification
NameDeoxycholic acid
CAS83-44-3
Synonyms3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oic acid
EINECS(EC#)201-478-5
Molecular FormulaC24H40O4
Molecular Weight392.58
Chemical Properties
Appearancewhite to off-white crystalline powder
alpha55 o (C=1, ETOH)
refractive index1.543
storage tempStore at RT.
Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Poison by intraperitoneal route. Moderately toxic by ingestion and intravenous routes. Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:  Xn
Xn:  Harmful
Risk Statements:  22-36/37/38-37-20/21/22
37:  Irritating to the respiratory system 
22:  Harmful if swallowed
36/37/38:  Irritating to eyes, respiratory system and skin
20/21/22:  Harmful by inhalation, in contact with skin and if swallowed 
Safety Statements:  26-36-37/39-22
22:  Do not breathe dust 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37/39:  Wear suitable gloves and eye/face protection


Toxicity
1.    

mmo-sat 20 mg/L

    MUREAV    Mutation Research. 158 (1985),45.
2.    

sln-smc 100 mg/L

    CRNGDP    Carcinogenesis. 5 (1984),447.
3.    

otr-ham:emb 7250 µg/L

    TOLED5    Toxicology Letters. 9 (1981),177.
4.    

orl-rat LD50:1 g/kg

    NAIZAM    Nara Igaku Zasshi. Journal of the Nara Medical Association. 33 (1982),71.
5.    

orl-mus LD50:1 g/kg

    NAIZAM    Nara Igaku Zasshi. Journal of the Nara Medical Association. 33 (1982),71.
6.    

ipr-mus LD50:130 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),323.
7.    

ivn-rbt LDLo:1000 mg/kg

    ZGEMAZ    Zeitschrift fuer die Gesamte Experimentelle Medizin. 52 (1926),779.

supplier list

Extrasynthese
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Cambridge Isotope
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Address: Cambridge Isotope Laboratories 50 Frontage Road Andover, MA 01810-5413
New Zealand Pharmaceuticals
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Shin Nippon Yakugyo Co., Ltd
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Roche Applied Science
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Aceto Corporation
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Chengdu Biopurify Phytochemicals Ltd
Tel:+86-(28)-66780410
Address: No.24 Yongfeng Road, Chengdu, Sichuan 610041,
Aktin Chemicals, Inc.
Tel:+86-(28)-85159085
Address: Yongfeng Plaza, No.52, Yongfeng Road, Hi-tech Zone, Chengdu, Sichuan 610041,
Trust & We Co., Ltd.
Tel:86-21-61551611
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Changde Yungang Biotechnology Co., Ltd.
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Address: Qiaonan Industrial Park, Changde, Hunan 415101,
Chemrio International Limited
Tel:+86-(574)-2789-1268, +86-13957895864
Address: Room 611-612 Wante Business Center, No.487 Yangmuqi Road, Hi-tech Park, Ningbo, Zhejiang 315040,
Suzhou Industrial Park Yacoo Chemical Reagent Co., Ltd.
Tel:86-512-62956016
Address: Suite 209 A3 Building 218, Xinghu Rd, Suzhou Industrial Park, SuZhou, Jiangsu 215125,
Watson International Ltd.
Tel:+86-(512)-55117610
Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,
Xilin Chemical Group Co., Ltd
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Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071,
Echem Chemical Technology Co., Ltd.
Tel:+86-(575)-86766255
Address: 99,Tashan Industrial Parks, Xinchang County, Zhejiang 312500,

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