Hexafluorocalcitriol cas no:83805-11-2
Synonyms: 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,26,26,26,27,27,27-hexafluoro-, (1a,3b,5Z,7E)- (9CI);(+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1a,3b,25-triol;26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitaminD3;F6-1a,25-Dihydroxyvitamin D3;Falecalcitriol;Flocacitriol;Flocalcitriol;Flocalcitrol;Fulstan;Hornel;Ro23-4194;ST 630;
NameHexafluorocalcitriol
CAS83805-11-2
Synonyms9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,26,26,26,27,27,27-hexafluoro-, (1a,3b,5Z,7E)- (9CI);(+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1a,3b,25-triol;26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitaminD3;F6-1a,25-Dihydroxyvitamin D3;Falecalcitriol;Flocacitriol;Flocalcitriol;Flocalcitrol;Fulstan;Hornel;Ro23-4194;ST 630;
Molecular FormulaC27H38F6O3
Molecular Weight524.65
refractive index1.504
Safety
Hexafluorocalcitriol (CAS NO.83805-11-2) is a poison by ingestion and intravenous routes. When Hexafluorocalcitriol (CAS NO.83805-11-2) is heated to decomposition, it emits toxic vapors of F−.
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
dog |
LDLo |
oral |
5ug/kg (0.005mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
GASTROINTESTINAL: NAUSEA OR VOMITING |
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996. |
mouse |
LD50 |
oral |
55ug/kg (0.055mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996. |
rat |
LD50 |
oral |
41700ng/kg (0.0417mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996. |
rat |
LDLo |
intravenous |
3ug/kg (0.003mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996. |