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Hexafluorocalcitriol cas no:83805-11-2

Synonyms: 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,26,26,26,27,27,27-hexafluoro-, (1a,3b,5Z,7E)- (9CI);(+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1a,3b,25-triol;26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitaminD3;F6-1a,25-Dihydroxyvitamin D3;Falecalcitriol;Flocacitriol;Flocalcitriol;Flocalcitrol;Fulstan;Hornel;Ro23-4194;ST 630;

Identification
NameHexafluorocalcitriol
CAS83805-11-2
Synonyms9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,26,26,26,27,27,27-hexafluoro-, (1a,3b,5Z,7E)- (9CI);(+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1a,3b,25-triol;26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitaminD3;F6-1a,25-Dihydroxyvitamin D3;Falecalcitriol;Flocacitriol;Flocalcitriol;Flocalcitrol;Fulstan;Hornel;Ro23-4194;ST 630;
Molecular FormulaC27H38F6O3
Molecular Weight524.65
Chemical Properties
refractive index1.504
Safety Data

Safety

 Hexafluorocalcitriol (CAS NO.83805-11-2) is a poison by ingestion and intravenous routes. When Hexafluorocalcitriol (CAS NO.83805-11-2) is heated to decomposition, it emits toxic vapors of F.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 5ug/kg (0.005mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: NAUSEA OR VOMITING
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996.
mouse LD50 oral 55ug/kg (0.055mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996.
rat LD50 oral 41700ng/kg (0.0417mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996.
rat LDLo intravenous 3ug/kg (0.003mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Kiso to Rinsho. Clinical Report. Vol. 30, Pg. 2695, 1996.

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