86329-79-5|Cefodizime disodiumProducts Supply - Chemical intermediates Network

Cefodizime disodium cas no:86329-79-5

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt, [6R-[6a,7b(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);

Identification

NameCefodizime disodium
CAS86329-79-5
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt, [6R-[6a,7b(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);
Molecular FormulaC₂₀H₁₈N₆Na₂O₇S₄
Molecular Weight628.64

Chemical Properties

AppearanceWhite to yellow crystalline powder

Safety Data

Safety

Low toxicity by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic vapors of NO_x and SO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 5gm/kg (5000mg/kg)	?	Drugs in Japan Vol. -, Pg. 667, 1995.
mouse	LD50	intraperitoneal	10500mg/kg (10500mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Journal of Toxicological Sciences. Vol. 13(Suppl,
mouse	LD50	intravenous	5gm/kg (5000mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Journal of Toxicological Sciences. Vol. 13(Suppl,
mouse	LD50	oral	28gm/kg (28000mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Journal of Toxicological Sciences. Vol. 13(Suppl,
mouse	LD50	subcutaneous	16500mg/kg (16500mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Journal of Toxicological Sciences. Vol. 13(Suppl,
rat	LD50	intraperitoneal	8800mg/kg (8800mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Journal of Toxicological Sciences. Vol. 13(Suppl,
rat	LD50	intravenous	7gm/kg (7000mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Journal of Toxicological Sciences. Vol. 13(Suppl,
rat	LD50	subcutaneous	15500mg/kg (15500mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Journal of Toxicological Sciences. Vol. 13(Suppl,
rat	LDLo	oral	20gm/kg (20000mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Journal of Toxicological Sciences. Vol. 13(Suppl,

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Cefodizime disodium cas no:86329-79-5

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