Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16a,17a)- cas no:146-48-5
Synonyms: Yohimban-16a-carboxylic acid, 17a-hydroxy-, methyl ester (8CI);Yohimbol-16a-carboxylic acid, methyl ester(6CI);(+)-Yohimbine;Aphrodine;Aphrosol;Corynine;Quebrachin;Quebrachine;Yohimbicacid methyl ester;Yohimbin;Yohimbine;trans-Quinolizidine yohimbine;
NameYohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16a,17a)-
CAS146-48-5
SynonymsYohimban-16a-carboxylic acid, 17a-hydroxy-, methyl ester (8CI);Yohimbol-16a-carboxylic acid, methyl ester(6CI);(+)-Yohimbine;Aphrodine;Aphrosol;Corynine;Quebrachin;Quebrachine;Yohimbicacid methyl ester;Yohimbin;Yohimbine;trans-Quinolizidine yohimbine;
EINECS(EC#)205-672-0
Molecular FormulaC21H26N2O3
Molecular Weight354.45
refractive index1.66
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard Said to be an aphrodisiac. Toxic by ingestion.
Risk R23/24/25
Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human systemic effects: ataxia, heart rate changes, paresthesia.Cases of poisoning have occurred from its use as an aphrodisiac. Upon local application it produces anesthesia. However, absorption of it can give rise to toxic symptoms, such as salivation, increased respiration, and diarrhea. With reference to the circulatory system, there may be a fall in blood pressure and sometimes myocardial damage, involving particularly the conduction system of the heart, with a resultant decrease in the efficiency of the heart. An adrenergic blocker used to treat arteriosclerosis and angina pectoris. Formerly used as a local anesthetic and mydriatic (pupillary dilator). When heated to decomposition it emits toxic fumes of NOx.
