57576-44-0|1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, (1R,2R,4S)-Products Supply

1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, (1R,2R,4S)- cas no:57576-44-0

Synonyms: 1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, [1R-(1a,2b,4b)]-;Aclacinomycin A;Aclacur;Aclarubicin;Antibiotic3082A;Antibiotic 77-3082A;Antibiotic MA 144A1;Jaclacin;NSC 208734;

Identification

Name1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, (1R,2R,4S)-
CAS57576-44-0
Synonyms1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, [1R-(1a,2b,4b)]-;Aclacinomycin A;Aclacur;Aclarubicin;Antibiotic3082A;Antibiotic 77-3082A;Antibiotic MA 144A1;Jaclacin;NSC 208734;
EINECS(EC#)260-824-3
Molecular FormulaC₄₂H₅₃NO₁₅
Molecular Weight811.87

Chemical Properties

refractive index1.629
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(a)

Safety Data

Hazard T
Risk R25
Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. An eye and subcutaneous irritant. When heated to decomposition it emits toxic fumes of NO_x.

Hazard Codes: T
Risk Statements:
25: Toxic if swallowed
Safety Statements:
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Toxicity

1.	eye-rbt 100 µg MLD	JJANAX Japanese Journal of Antibiotics. 33 (1980),453.
2.	dnd-rat:lvr 6300 nmol/L	MOPMA3 Molecular Pharmacology. 14 (1978),290.
3.	cyt-rat-ipr 15 mg/kg	MUREAV Mutation Research. 260 (1991),215.
4.	orl-rat LD50:58,560 µg/kg	JJANAX Japanese Journal of Antibiotics. 33 (1980),138.
5.	ipr-rat LD50:17,930 µg/kg	JJANAX Japanese Journal of Antibiotics. 33 (1980),138.
6.	scu-rat LD50:20 mg/kg	JJANAX Japanese Journal of Antibiotics. 33 (1980),138.
7.	ivn-rat LD50:25,710 µg/kg	JJANAX Japanese Journal of Antibiotics. 33 (1980),138.
8.	orl-mus LD50:30,100 µg/kg	ANTBAL Antibiotiki. 30 (1985),918.
9.	ipr-mus LD50:16,100 µg/kg	ANTBAL Antibiotiki. 30 (1985),918.
10.	scu-mus LD50:22,100 µg/kg	ANTBAL Antibiotiki. 30 (1985),918.
11.	ivn-mus LD50:16,500 µg/kg

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1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, (1R,2R,4S)- cas no:57576-44-0

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